Doctor's Best Fully Active Folate 400 with Quatrefolic®️ contains Quatrefolic®, the glucosamine salt of (6s)-5-methyltetrahydrofolate, the most bioavailable form of folate, that provides greater stability and water solubility. Our bodies cannot synthesize folate and due to its water-soluble nature, the body stores folate to a limited extent. Folic acid, and food folate, needs to be converted to its metabolically active form to be utilized by the body. Quatrefolic® is the metabolically active folate, making it more efficient than folic acid for maximized benefits! Folate is an essential vitamin to support DNA, proper cell division, cardiovascular, mental and emotional well-being. Vitamin C is included for added stability.