Natural Lutein & Zeaxanthin Reduce Eye Fatigue & Support Prolonged Screen Time. Doctor's Best Lutein with OptiLut® supplies OptiLut® which is produced under a patented extraction process from Marigold flowers, and contains highly bioavailable all natural Lutein and Trans-Zeaxanthin.  Lutein and zeaxanthin are the major carotenoids found in the blood, and are highly concentrated in the retina of the eye. Lutein and zeaxanthin helps neutralize free radicals to support healthy visual function, macular health, and cognitive acuity.